nude mice

nude mice
Strains of athymic mice bearing the recessive allele nu/nu which are largely hairless and lack all or most of the T-cell population. Show no rejection of either allografts or xenografts; nu/nu alleles on some backgrounds have near normal numbers of T-cells.

Dictionary of molecular biology. 2004.

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  • Nude mouse — A nude mouse A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype, or main outward… …   Wikipedia

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